Addiction Treatment Forum reports on substance abuse news of interest to opioid treatment programs and patients in methadone maintenance treatment.

Rx Methadone & Safety

Dosing

Cardiac Concerns

Drug Interactions

Safety

Dosing

AATOD Guidelines for Guest Dosing

http://www.aatod.org/policies/policy-statements/aatod-guidelines-for-guest-medication/

 

Methadone Dosing & Safety in the Treatment of Opioid Addiction
Stewart B. Leavitt, MA, PhD; Editor. Released September 2003.
PDF PDF available here for download <click here…> (312KB, 8pp)

 

When "Enough" is Not Enough: New Perspectives on Optimal Methadone Dose
Stewart B. Leavitt, MA, PhD, Marc Shinderman, Sarz Maxwell, Chin B. Eap, Phil Paris; Mount Sinai Journal of Medicine, Released in 2000.
PDF PDF available here for download <click here… > (91KB, 8pp)

 

Clinical Diagnostic Tool for Guiding Methadone Treatment of Opioid Addiction
ODAS - Opiate Dosage Adequacy Scale... from Heroin Addiction & Related Clinical Problems. 2004;6(3)39-49. Distributed with permission of the journal.
PDF PDF available here for download <click here…> (452KB, 12pp)

 

Cardiac Concerns

Cardiac Considerations During MMT
Stewart B. Leavitt, MA, PhD; Editor & and Mori J. Krantz, MD, FACC.

Released October 2003.
PDF PDF file available here for download <click here…> (200KB,6 pp)

 

Methadone's Role in Torsade de Pointes Questioned
Stewart B. Leavitt, MA, PhD; Editor.

Released September 2002.
PDF PDF file available here for download <click here...> (250KB, 5pp)

 

Does Methadone Maintenance Treatment Affect Heart Health?

Released 2001,
Stewart B. Leavitt, MA, PhD; Editor.

Released June 2001.
PDF PDF file available here for download <click here…> (PDF file 88KB, 6pp)

 

Drug Interactions

American Journal on Addictions - Special Issue on Methadone Interactions With Other Medication and Abused Substances
March/April 2010.

PDFArticles available for purchase at:
http://www3.interscience.wiley.com/journal/123215724/issue

 

HIV Drug Interactions

http://www.hiv-druginteractions.org/ - This informative and educational HIV resource is valuable for healthcare professionals, scientific researchers or anyone with an interest in HIV therapy. You can find reports on recent news and hot topics in HIV pharmacology, discover comprehensive information, and advice on drug interactions. Access checked November 20, 2013.

 

Medscape Methadone Drug Interaction Checker
http://reference.medscape.com/drug/methadose-dolophine-methadone-343317#3 - Access checked December 26, 2013.

 

Methadone-Drug* Interactions – 3rd Edition
(*Medications, illicit drugs, & other substances)

Stewart B. Leavitt, MA, PhD; Editor. Released November 2005.
PDF PDF available here for download <click here…> (660KB, 31pp)

 

Safety

VERMONT STATEWIDE OPIOID ANTAGONIST COMMUNITY ACCESS PROGRAM INTRANASAL NALOXONE ADMINISTRATION TRAINING MODULE
Vermont Department of Health

PDF PDF available at: http://healthvermont.gov/adap/treatment/naloxone/documents/naloxone_pilot_intranasal_admin_presentation_slidesonly.pdf

 

SAMHSA Opioid Overdose Prevention Toolkit SAMHSA Opioid Overdose Prevention Toolkit SAMHSA Opioid Overdose Prevention Toolkit

Released August 2013.

The kit contains a series of brochures and can be accessed at: http://store.samhsa.gov/product/Opioid-Overdose-Prevention-Toolkit/SMA13-4742

 

CLINICAL GUIDELINES FOR THE USE OF BENZODIAZEPINES AMONG PATIENTS RECEIVING MEDICATION ASSISTED TREATMENT FOR OPIOID DEPENDENCE

Baltimore Substance Abuse Systems, Inc.

May 2013.

PDF PDF available at: http://www.bhsbaltimore.org/site/wp-content/uploads/2013/09/Benzo-Guidelines-FINAL-May-2013.pdf

 

SAMHSA Dear Colleague Letter on State Prescription Drug Monitoring Programs (PDMPs)

September 27, 2011.

PDFPDF available here for download <click here... > (1.04MB,12pp)

 

Research Article - Benzodiazepine Use and Misuse Among Patients in a Methadone Program

Chen et al.: Benzodiazepine Use and Misuse Among Patients in a Methadone Program. BMC Psychiatry 2011 11:90.

PDFPDF available here for download <click here... > (170KB,7pp)

 

International Harm Reduction Association (IHRA) "50 Best" Collection on Overdose

Available online August 2009.

http://www.ihra.net/overdose?utm_source=IDPC%2BMonthly%2BAlert&utm_campaign=9a0ed519d3-&utm_medium=email

 

Medication-Assisted Treatment Patient Safety Presentations and Conference Videos
Available online from Institute for Research, Education, and Training in Addictions (IRETA).

http://ireta.org/node/630

 

SAMHSA Emerging Issues in the Use of Methadone Advisory
Spring 2009.
PDF PDF available here for download <click here…> (514KB, 8pp)

 

"Drug Overdose Reduction Act" 2009

Released June 12, 2009.

PDF PDF file available here for download <click here…> (51 KB, 12pp)

 

FDA/SAMHSA Methadone Safety Education Program - Follow Directions: How to Use Methadone Safely

From the Food & Drug Administration (FDA) and Substance Abuse Mental Health Service Administration (SAMHSA).

Released April 2009.

These public education materials (brochure, fact sheet, and poster) were designed specifically for this campaign to inform patients and healthcare professionals that methadone is a safe and effective treatment when used exactly as prescribed. The materials are available in English and Spanish.

 To download or order printed copies <click here…>

 

GAO Report - Methadone-Associated Overdose Deaths

From U.S. Government Accountability Office

Released March 2009.

PDF PDF file available here for download <click here…> (1.73 MB, 55pp)

 

Preventing Overdose Deaths: Strategies for Combating a National Crisis

Drug Policy Alliance.

Released March, 2009.

 PDF file available for download <click here…> ( 24pp)

 

AT Forum Summer 2007 Newsletter Methadone Overdose in MMT - What to know. How to prevent it. What to do if it happens.

PDF PDF file available here for download <click here…> (8pp)

 

Methadone Diversion, Abuse, and Misuse: Deaths Increasing at Alarming Rate
From U.S. Department of Justice National Drug Intelligence Center

Released November 2007.

PDF PDF file available here for download <click here…> (20pp)

on Methadone Overdose Report

Methadone Mortality - A Reassessment July 2007
From CSAT/DPT. Released October 2007.

PDF PDF file available here for download <click here…> (426 KB, 48pp)

 

Methadone-Associated Mortality: Report of a National Assessment. From CSAT/DPT, 2004.
PDF PDF file available here for download <click here…> (428KB, 60pp)

 

The Safety of Methadone, LAAM, Buprenorphine
Stewart B. Leavitt, MA, PhD; Editor. Released 2001.
(MS Word Document available here for download <click here…> (48KB, 22pp)
Note: Also see, AT Forum, Spring 2001; 10(2)

 

FDA Drug Safety Information for Patients and Providers
Patients and providers can now go to a single web page to find information on a variety of prescription drugs. Information is available on: drug labeling, including package inserts; drugs that have a risk evaluation and mitigation strategy (REMS); warning letters and alerts; and regulations and guidance documents.
HTML file available online <click here... >

 

Guide to Treating Drug Emergencies

Drug and Alcohol Abuse: A Clinical Guide to Diagnosis and Treatment; 6th ed., Marc A. Schuckit, MD provides an overview of drug classifications and mechanisms, and covers the pharmacology and mental/physical effects of alcohol, depressants, stimulants, opioids, hallucinogens, cannabis, and more. Most critical, there is an emphasis throughout the book on how to deal with emergency medical problems related to drug abuse, addiction, and overdose.

Schuckit recommends skimming all of the chapters covering the many drug classes. From there, the book can serve as a handbook, kept nearby for easily-accessed advice on dealing with drug-related crises or confirming suspected drug-induced symptomatology appearing in clinical settings.

Drug and Alcohol Abuse: A Clinical Guide to Diagnosis and Treatment; 6th ed. is from Springer. Available online from www.amazon.com ($79.89 + free shipping) and at other booksellers.

Links checked March 17, 2014.

All URL links noted in documents at this AT Forum website were active at the time of publication.  Since the Internet is constantly changing, some linked sites may have moved or become inactive, which is beyond the control of AT Forum.